Welcome to Novellus

A new American restaurant in the heart of Main Street St Charles

Novellus is a new American restaurant on Historic Main Street in St Charles. The name Novellus comes from the Latin for the word "novel" in which we attempt to play off our literary theming and innovative menu. We strive to create a new type of dining destination that is vibrant, spacious and lives up to its name.

Serving a multitude of different options such as our weekend brunch with bottomless flavored mimosas and tiered spicy bloody marys, or maybe come instead for lunch and have our "Choose Your Own Adventure" lunch special.

If you are more the dinner type, enjoy our large selection of small plates and crafted cocktails, and if nothing else join us for happy hour every weekday from 3-6pm for specials on everything from finger foods to rare whiskeys.

Next time you want to find a new restaurant on Historic Main Street St Charles, stop in to Novellus to enjoy a delicious dinner in our dining room, brunch on our patio, or have a crafted cocktail or rare bourbon in our lounge.

Find Us On Main Street

201 N Main St
St. Charles, MO 63301
‪(636) 486-7022‬

Just enjoyed a delicious brunch at Novellus! Best Eggs Benedict and Biscuits and Gravy I’ve ever had, but the highlight of my experience was the Bloody Mary – outstanding! My compliments to their Chef and their Bartender.

Barb F

I wish I would have thought of taking pics of our meals before we dug in 🙁 Not only did they look amazing, but they tasted even better. The vibe here would be perfect for evening cocktails. Highly recommend.

James C

If you love crafted cocktails, amazing food, or need a new spot in St Charles for brunch, then Novellus is for you!

Jo O

My friend robby completed the Dantes Inferno. He had to lay on the floor when waiting for the last 5 mins to be over. It was great.

Shantelle Mueller

This place has become my go to! I love they welcome pups on the patio still! I do wish they had more gluten free options, but you can make do with what they do have!

Allyson Parry

AWESOME atmosphere, food, beverages, and service! Price point surprisingly decent for the quality, too. Went here with a friend last night because we’re both big literary nerds and Novellus did not disappoint. The vibe is great in the dining area, and I was pleasantly surprised at how accommodating the staff were. We sat at a two-person table surrounded by books, and I loved every minute of it.

The Abberwocky

Really enjoyed this new place. They serve a lot of their food Tapas style, so we could all share several items.

Christen N

The Wedge salad with horseradish ranch. I dream about it, that’s how good it is. Novellus also has some of the best brunch and mimosas around.

Cody Miller

Fantastic food and service! Fun small plates style. We got 4 different dishes and none disappointed. Stumbled upon this place while visiting from out of town and so glad we did!

Katie Webb

There were so many things that were enjoyable eating here. The cocktails were fun and tasty while ranging from sweet to dry with plenty of options we both wanted to choose.

Joshua D


201 N Main St
St. Charles, MO 63301

Our Hours

Mon-Fri 11am – 10pm
Sat 10am – 10pm
Sun Brunch 10am – 3pm